During an IVF cycle, an embryologist is responsible for the 6-day process to create and select the most promising embryos. However, looking at the embryos this morning it turned out that my embryos had not quite reached blastocyst phase. The first Home Pregnancy Test I did was 5 days after my day-5 blastocyst transfer, which was positive. Morula transfers are marginally more successful than 3 day transfers and marginally less successful than a blasto transfer but from what I remember (from research I did myself when . Hi All, This is my first time posting and was hoping for some other stories like mine. These success rates include all cycles in 2020 where: women used their own eggs for IVF treatment. @KnockingForty best of luck for your transfer. If you have a Day-3 transfer, you should have one or more embryos to transfer, and if you have a Day-5 transfer, you should have one or more blastocysts to transfer. My sweet baby was transferred on Day-5. stage 3) by Day 6 . This means that high pregnancy rates can be achieved from the transfer of fewer embryos on day 5 with a reduction in the risk of high-order multiple gestations. If you decide to have your embryos frozen or take part in a fresh embryo . My RE advised the chances of success with a morula are about 15% vs 30% for a blast. Unfortunately, this embryo did not implant either. After the first 24 hours, (Day 1) the embryo has divided into 2 cells. Morula, 160 microns. Cal;l me if this does not work out I have some thoughts. So by day 5, my doc explained that they like to see the embryos at the blastocyst stage. So you see your morula could become a blast at any point just because it's not a blast yet doesn't mean it's a whole day behind it may mearly be an hour or 2 behind. Im feeling really negative about this and already feeling like it . This is also one to five days after a blastocyst transfer in the recipient. Days Past Transfer (DPT) Embryo Development. The recently formed blastocyst begins to hatch out of its shell. . A single cell embryo is called a 2PN zygote (for 2 pronuclei). Everything about that round was shit but it . Hi all I am new in this forum I had EC yesterday I had 5 mature eggs collected and this morning i got a call from embryologist that only 1 got fertilised in a good way so he asked me to have a day 2 transfer now I never had day2 I have had day3 long time ago and day5 fresh and frozen this January which was failed cycle. The Day 5 embryos were evaluated according to Gardner and Schoolcraft. On day 5 (Mon), we got the news that all 5 eggs were still alive but were growing at a slower rate. Please help 07/16/2017 14:06 Subject: Morula transfer on day 5 . On Saturday (the 14th), I had my retrieval. I froze it and transferred it on a frozen cycle and when they thawed it, it quickly hatched and became a fully hatched blast at transfer. we retrieved 15, 10 fertlized and only 4 . poor quality blasts) have roughly 1/2 of the chance of a good quality embryo. In other words, she will be able to confirm whether she is pregnant and the treatment has been successful.. We see significantly higher blastocyst implantation and pregnancy rates as compared to what we see with day 3 embryos. Waitingformiracles13 Posted 1/26/18 Of 11 embryos (5 which were optimum at day 3), there were two at the early blastocyst phase (or possibly still morula phase). We had 3 eggs fertilize in total. Morula's and question about day 5 transfers. Day 1. We had 3 eggs fertilize in total. My doctor wasn't optimistic either but we have boy/girl twins! If they could survive till 5days in petri dish...they got all the chances to survive in uterus. It is important to point out that by culturing embryos . Determining the best day for the embryo transfer actually depends on the progression of . Somewhat subjective — so two different embryologists may have two . Not subjective — 8 or higher is ideal) Quality of cells. Day 3 transfer was . Embryo Quality and Failed IVF - 5 days in the IVF laboratory. Here's the data: Oron (2014) looked at single embryo transfers in women <40 years of age: Good quality blasts (≥3BB) a live birth rate of 41% was achieved Some patients are better served having . I had a day 5 morula transferred back in 2018 and had my DD who is now 2.5. Cells divide into two groups: Inner cell mass - The group of cells that will become the embryo . A day 5 morula can become a day 6 blast but not high probability that is is good quality. When a couple has high-quality embryos available for transfer on day 5 and they are offered the options of transferring one embryo with a 50% expectation for pregnancy (almost all singles) or two embryos with an 75% expectation for pregnancy (about 38% twins, 60% single, and 2% triplets), most couples choose to transfer two embryos. 1. At this stage, he was expected to be a . My partner and I did an embryo transfer this morning. Day 3 embryos are graded according to two criteria: Number of cells. KitKatKates Fri 22-Mar-19 16:03:11. . The Dr. suggested 3 egg transfer with the hope that at least 1 will catch. Sending some good luck wishes your way. While the cell number is objective, the score for appearance is subjective using a score of 1-4. They were still in the Morula stage. 1. . At the time, I remember thinking he just wanted our money (but 2 years later, I'm certainly less cynical) Well, our first cycle was a complete shock and very disappointing. Both had 4 cells, all cells were the same size and each cell had 1 nuclei! By Day 5, the embryo, now called a blastocyst, is about 70-100 cells. We had 12 embryos progressing but sadly none were in a viable condition for transfer day 5 except for one murola. The latest version of the American Society for Reproductive Medicine (ASRM) Practice Committee publication states that "a single . Five eggs were retrieved, 4 fertilized, and 3 were transferred. Any more success stories. Morula. Hello. I am with shady grove and this is my third ivf. Stay Positive! Success Stories Motherhood at the age of 64 I am Mrs Our first attempt at IVF gave us a total of 8 blastocysts, however all of them were either Day 6 or Day 7 5% were transferred on day five, 4 Compared to embryo transfer at an early development stage (day 2 or 3) the odds are increased by around 7% (Source DIR Jahrbuch - German IVF-Registry Annual . Stellabelle #4 Validating 4 posts Posted 20 March 2008 - 07:55 AM Thank you to those who have replied to my post about a Morula day 5 transfer. Search: Day 7 blastocyst success stories. An embryo that continues to grow to Day 5 becomes a blastocyst with hundreds of cells. Here are our live birth success rates for day 5 blastocyst transfer cases: We have done blastocyst culture and transfer since 1998. Hi ladies, I have had a day 5 morula trasnfer on Monday and i am just looking for anybody that has positve or negative posts about going throguh this. The webinar is hosted by Laura Van Os, an embryologist from IVF Spain. Some of the advantages of performing an embryo transfer at the blastocyst stage, instead of on Day 2-3 of embryo culture are: Better selection of the fastest growing embryos. Embryo Transfer Allowing the embryos to grow from Day 3 (cleavage stage) to Day 5/6 (blastocyst) allows us to select the embryos with the highest chance of success. To my surprise 2 were great quality. Now, for women less than 35 years old, 47.2% of IVF cycles resulted in the birth of a single baby, while for women over 40 using their own eggs, 7.2% of IVF cycles resulted in the live birth of a single baby. Grade C blastocyst stage (Day 5+) success rates. Kristiec78 28/05/13. We received a batch of 6 eggs. 2. very little chance on question 2. . At day eight, the embryo will still sink in fluid, but . However they were good looking morulas with no fragmentation per dr.at fertility clinic but no blastocyst as of yet. I had a morula transferred day 5 this week - bit of a rollercoaster of emotions- keep going from feeling hopeful to very unoptomistic. Approximately 50% of the good quality embryos on day 3 will not survive until day 5, although those embryos that do survive have a good chance of implantation. Today I received the day 5 update and all are still morula stage. My morulas were arresting, but my cycle buddy also had no blasts, transferred only one morula on day 5 (her transfer was immediately after mine), and she got her bfp. By day 3 we still had 3 but 2 of them had only 3 and 4 cells respectively - the other was 7 which is considered "normal." By Day 3, it is about 4-8 cells, and is referred to as a multicell embryo. I went for my day 5 embryo transfer today. Bottom line: Transferring 1 day 5 embryo (blastocyst) has almost the same pregnancy rate as transferring 2 day 3 embryos, and almost no chance of twins (compared to a 20% chance of twins transferring 2 day 3 embryos). The sequence shown below shows an 8-cell embryo on day 3 (#1) in which the cells are beginning to press up against one another (see 2 cells flattening against each other). Official diagnosis: Unexplained IF. We let it grow to day 6 and by the afternoon of day 6 it was an expanded blast. - Day 0: Mature egg is inseminated - Day 1: Fertilization assessment - Day 2: Embryo is between 2-4 cells - Day 3: Embryo is between 6-8 cells - Day 4: Embryo is compacting ( cell-to-cell adherence) or Morula (16-32 cells, cells adhered ) or cavitation (CAV) - Day 5-7: Embryo shows early cavitation (CAV) or becomes Blastocyst To summarize, grade C embryo success rates (ie. My current pregnancy was a morula on day 5. The success of the embryo transfer will depend on the quality of the embryos, but also on the state of the endometrium and its receptivity at the time of the transfer. Cleavage stage embryos are graded using 2 criteria: the number of cells in the embryo and their appearance under a high-power microscope. As I have said before, it depends on the number of embryos on day 3 with 8 cells. The Dr. had checked in the morning and by 2 pm, 1 egg was starting to show indications of moving to the next stage. On day 5 (Mon), we got the news that all 5 eggs were still alive but were growing at a slower rate. The first one was a slow grower too, went to day 6, but with research I found out that it wasn't a bad thing and that more often than not it's a female embryo. By day eight, the embryo has increased in size to 800 microns or more and is termed a large expanded blastocyst. A: An embryo that has been growing for 3 days typically has 8 cells. Transferring 2 day 5 embryos has a higher pregnancy rate and a 30 to 40% chance of twins. Subject: Re:transfer of 3 embryos, mediocre quality - success stories? The freshly fertilized embryo is called a zygote. We mean it. I took another test 8 days after my day-5 blastocyst transfer (2 days ago) and it was much darker in color, so things are looking even more promising. This stage is the first time we see the cells begin to organize themselves. My doctor told me that the success rate with morulas on day 5 is just slightly less than blastocysts on day 5..some embryos just need an extra day to get to the blastocyst stage. The Dr. suggested 3 egg transfer with the hope that at least 1 will catch. Today is 07-07-10. Laura tries to answer the question why IVF cycles fail and if modern science can do anything about it. This means that high pregnancy rates can be achieved from the transfer of fewer embryos on day 5 with a reduction in the risk of high-order multiple gestations. Official diagnosis: Unexplained IF. Day 5 or even later on day-4 brings the transformation of the ugly duckling—the morula—into a swan—a blastocyst, consisting of anywhere from 30 to 200+ cells. Some are slow growers, but that does not matter at all. The cells of the morula continue to divide, developing into a blastocyst. However, in cases where only morula/compacting embryos are available by Day 5, extending culture until FEB are achieved and then performing subsequent FET will result . (If you didn't have a day-5 transfer, your implantation window is 6 to 10 days after egg retrieval. Wider implications of the findings: Fresh transfer of embryos that begin blastulation on Day 5 results in similar outcomes to the transfer of FEB originating from the same cohort. All the cells are doing the same job and are identical at this point. Probably less than three, with 8 cells on day 3. This cycle also yielded 3 eggs, 2 fertilized, and only 1 made it to transfer as a day 5 morula. Day 2. Well just like last cycle got to the clinic today to learn that 16 of our 18 embryos arrested between day 4-5, there were two embryos still growing but at day 5 they were only morula, one looks like it's starting to get the "fluid" like spot but just so devastated. Fragmentation: Embryos with no or little fragmentation are labeled grade A, those with more than 10% fragmentation are grade B, and the ones with more than 25% and 50% fragmentation are labeled C and D grade respectively. An embryo might undergo developmental arrest because of : 1) Sub-optimal culture conditions. Here's what research conducted in 2019 shows for fresh and frozen embryo transfer success rates: Higher quality embryos are associated with a 79% live birth rate with good quality at 64%. The 2PN zygote divides into an embryo (2-4 cells), the "morula" approx. I was absolutely stunned when I did the pregnancy test. Im searching frantically all over google and am really reading mixed posts, i guess as my doc said i should stay positive and stop looking . but if I'm going to end up doing a morula at day 5, I'd prefer to do day 3 and get the embryos out of the lab. . Day 5. They were still in the Morula stage. A summary timeline of normal implantation follows: Day 0: the egg is fertilized high up in the fallopian tubes and forms the zona pellucida. IVF#2 . . We had no blastocytes which was hugely disappointing. . Today is my 41st birthday. 5 day morula transfer - any BFP success stories? I am 32. . Trying concieve since 40 1st IVF/ICSI age 41 : Gonal F 300; 3 eggs; 2 fertilised; transfer day 5; BFN 2nd IVF/ICSI age 42 : Menopur 425; 2 eggs; 2 fertislised; transfer day 5; BFN 3rd IVF age 42 : Short protocal Menopur 375; so far on Day 4 scan 2 focilles again and some very small ones Dont know what Worth it though because I've seen lots of woman on FF (fertilityfriendonline) tell success stories. So we're trying to see if anyone had any success with a day five morula transfer. Our egg donor is an anonymous, healthy, 22 year old woman from a frozen egg bank. . Day 1-4: the egg continues to move down the fallopian tube and . My husband and I are 1st time ivf'ers and today was supposed to be our day 5 transfer of what we were hoping were going to be blastocyst.
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